1. Introduction
6-Aminocaproic acid powder 99 percent 60-32-2, also known as aminocaproic acid, aminocaproic acid, ε-aminocaproic acid, and antifibrinolytic acid, is a commonly used anti-plasmin hemostatic agent for SAH. It's a kind of white crystal powder. with melting point 204-206 degree . It's easily soluble in water, slightly soluble in methanol, insoluble in ethanol and ether. It's odorless and has a bitter taste.
2. Specification
ANALYSIS | SPECIFICATION | RESULT |
Assay （C6H13NO2） | Greater than or equal to 98.50 percent calculated on anhydrous basis | 99.9 percent |
Appearance | White crystalline powder | Complies |
Solubility | Freely soluble in water, almost insoluble in chloroform or ether. | Complies |
Identification | The infrared absorption spectrum is concordant with the reference spectrum | Complies |
Melting point | 204-207 degree | Complies |
Clarity of solution | Should be conform | Complies |
PH | 7.5-8.0 | 7.8 |
Calciumion | Should be conform | Complies |
Chloride | Less than or equal to 14ppm | Complies |
Heavy metal | Less than or equal to 10ppm | Complies |
Loss on drying | Less than or equal to 0.5 percent | 0.05 percent |
Sulphate | Less than or equal to 0.01 percent | Complies |
Residual on ignition | Less than or equal to 0.1 percent | 0.05 percent |
Heavy metal | Less than or equal to 10 ppm | Complies |
Conclusion | Conform with In House Standard | |
Packing Storage | Cool and Dry | |
Shelf life | 2 years when properly stored | |
3. Flow chart
4. Test Report
5. Test Method
Dissolve 0.100 g in 20 mL of anhydrous acetic acid R.
Using {{0}}.1 mL of crystal violet solution R as indicator, titrate with 0.1 M perchloric acid until the colour changes from bluish-violet to bluish-green. 1 mL of 0.1 M perchloric acid is equivalent to 13.12 mg of C6H13NO2.
6. Function
6-Aminocaproic acid powder 99 percent 60-32-2, is a commonly used anti-plasmin hemostatic agent for SAH. It has anti-fibrinolytic effect and can interact with plasmin Prokinetic Chemicalbook produces competitive inhibition, which inhibits the conversion of plasminogen into plasmin. It also has a weak direct inhibitory effect on plasmin, slowing down the cleavage of fibrin into peptides and amino acids.
7. Application
(1).Hemostatic drugs. It has obvious effect on some severe bleeding caused by increased fibrinolytic activity. Suitable for bleeding or local bleeding during various surgical operations.
(2).It is also used for hemoptysis, gastrointestinal bleeding and obstetrics and gynecology hemorrhagic diseases.
(3).Used as a biochemical reagent.
8. Stability and Safety
Stability:
Stable under proper conditions(room temperature). Stability Data Sheet is available upon your request.
Safety:
According to GARS(Generally Recognized As Safe) Notice of US, it is safe for human consumption.
9. Certificate
Over the years, we have been committed to the product manufacture optimization and quality system establishment. We've set up the quality management system and obtained certificates of it.
10. Exhibition
We often attend international exhibitions, including CPhI, FIC, API, Vitafoods, SupplesideWest.
11. Our Customers
We've established business relationship with Abbott, Unilever, Shiseido, KANS and SIMM, etc.
12. Customers'Review
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